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Although ConfocalVR and ChimeraX are free for non-profit entities, that is not true for commercial firms.
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The VR software itself can also be expensive. Oculus Rift suggests using VR-compatible computers ranging from US$850 to nearly $3,100 it recommends at least 8 gigabytes of memory and a high-end graphics card. In some cases, a new graphics card will add sufficient computing power, “but in general you’re probably going to buy a new computer”, says Tom Skillman, director of informatics and research technology at Benaroya and one of the creators of ConfocalVR. VR is computationally intensive, both because each eye must see a different image to produce a 3D effect, and because those images must refresh rapidly.
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Oculus Rift and Vive both run using the Windows operating system, although Vive is also compatible with MacOS X. InViewR works only with Oculus Rift, whereas ChimeraX and ConfocalVR work with both. That said, not every tool is compatible with all headsets. “I don’t think there’s a clear winner at this point,” says Tom Ferrin, one of the developers of ChimeraX, whose lab at the University of California, San Francisco, specializes in molecular-visualization tools. Researchers and gamers have their preferences, but the differences between Oculus Rift and Vive are small. But in VR, “you can just walk through the hydrogens at different angles and distances, and quickly detect some important interactions”.Īlthough inexpensive options are available, most visualization tools work only with the priciest headsets - such as Facebook’s Oculus Rift, and the Vive from Taiwanese electronics company HTC - because they can track the user’s head and handheld-controller movements in 3D space. A computer monitor is “so messy when you turn on a lot of atoms for visualization”, Cortopassi says. ‘Walking’ in virtual space through a network of hydrogen bonds helped Cortopassi to understand how certain mutants of a protein could stymie drugs that target it. ChimeraX is a molecular-visualization tool for proteins and other structures, which added support for VR headsets in November 2016. Wilian Cortopassi, a postdoctoral researcher at the University of California, San Francisco, has also gained scientific insights from VR explorations. The nucleus was actually deforming and moving around the lysosomes. “It looked as if part of the lysosomes of the cell had moved into the nucleus, which didn’t really make sense to us.”īut ConfocalVR, a tool developed at Benaroya that uses VR to visualize images from confocal microscopes, made what was really happening “jump out within seconds”, Lacy-Hulbert says. But he was perplexed by some of the 2D images he was getting using conventional microscopy. He is particularly interested in lysosomes - structures that help to clean up the insides of cells.
Yet some researchers say that the technology has provided new insights.Īdam Lacy-Hulbert is a principal investigator at the Benaroya Research Institute in Seattle, Washington.
Their numbers are relatively small: VR and AR remain niche tools for scientific research. Others have sought cheap, smartphone-based headsets, which use a smartphone screen as the goggles, to increase public understanding of their work. Some scientists see VR and AR as more intuitive to use than conventional flat screens for viewing complex 3D structures. A similar surge has emerged in augmented reality (AR), a related technology that uses a see-through visor or smartphone screen to layer objects on top of real surroundings. VR isn’t new, but interest in the technology has boomed since 2016, when gamers and a handful of scientists introduced several high-quality, relatively inexpensive commercial headsets to the public.
Looking at a cell in VR is “as close as you can get to touching” such a minuscule structure, says Sebastian Konrad, product manager for VR at Arivis, a life-sciences software company in Munich, Germany, that developed this particular VR visualization tool, called InViewR, and who helped to arrange my demonstration of it. Using hand controllers, I dissect the cell layer by layer, excavating with a flick of the wrist to uncover tiny, specialized structures buried beneath the surface. I stick my head inside to explore its internal structure. A cell fills my visual field, and as I crane my neck, I can see it from several angles. As I put on a virtual-reality (VR) headset, the outside world disappears.
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